Science-first brain health

Plant-based science to keep you, you.

BNS Neuro studies natural compounds that interfere with tau aggregation, one of the key protein changes behind Alzheimer’s disease and related dementias. We develop supplements grounded in laboratory evidence, and we explain that evidence openly.

Why it matters

Dementia is common.
Much of the risk is not fixed.

What is dementia?
1 in 10Americans aged 65 and older are living with dementia.Manly et al., JAMA Neurology, 2022
1 in 3Americans aged 90 and older are affected.Manly et al., JAMA Neurology, 2022
14modifiable risk factors identified by the Lancet Commission.Livingston et al., The Lancet, 2024
~45%of dementia cases could, in theory, be prevented or delayed by addressing them.Livingston et al., The Lancet, 2024
The biology

Two proteins, one complicated story

Alzheimer’s disease involves two misbehaving proteins. Amyloid-β clumps into plaques between neurons. Tau, which normally stabilizes the neuron’s internal skeleton, twists into tangles inside them and can spread from cell to cell.

Most approved drugs target amyloid. Tau tangles, however, appear in Alzheimer’s disease, frontotemporal dementia, CTE and other tauopathies. That shared role is why we focus on tau.

Tau & amyloid, explained
Abstract illustration of the prefrontal cortex in the BNS Neuro brand style
Our research

From screening to behavior

Every candidate compound moves through a staged, preclinical research pipeline built around tau.

See our approach

Screen

Natural compounds are screened in tau biosensor cells that light up when tau aggregates.

Inhibit

Promising flavonoids are tested for their ability to block tau fibril formation.

Model

Extracts are applied to cell models seeded with Alzheimer’s-derived tau.

Validate

Long-term oral dosing in an established Alzheimer’s mouse model, with memory testing.

Updated continuously

Just published

The newest peer-reviewed papers on Alzheimer’s disease, dementia and tau, straight from PubMed-indexed journals.

Open the full feed

Coming soon

Our first formulation

We’re preparing our first plant-based supplement for launch, developed around the tau research on this site. Join the list to hear first when it’s available.

Join the waitlist